Introduction
Flagship public health intervention under National Health Mission (NHM), Child Health Division, Ministry of Health & Family Welfare (MoHFW), Government of India
Launched in 1970s; revised & strengthened as part of RMNCH+A strategy to combat Vitamin A deficiency (VAD)
VAD is major preventable cause of childhood blindness, increased morbidity & mortality from measles & diarrhea
Provides prophylactic mega-dose oral Vitamin A to prevent subclinical & clinical deficiency in under-5 children
Universal coverage approach – no screening required; biannual fixed-day strategy
Objectives
Prevent & control Vitamin A deficiency disorders (night blindness, Bitot’s spots, corneal xerosis/ulceration, keratomalacia)
Reduce under-5 mortality & morbidity (especially measles case-fatality, diarrhea severity)
Improve child survival, growth & immunity
Achieve >90% coverage of 9 doses in 9–59 months age group
Integrate with routine immunization, deworming, growth monitoring & nutrition programs
Target Group & Dosage Schedule (Current NHM Guidelines)
All children 9–59 months (universal coverage)
Total 9 doses till 5 years of age:
Age Group Dose (IU) Volume Timing / Frequency 9 months 100,000 1 ml With MR-1 vaccine 16–23 months 200,000 2 ml With DPT booster / MR-2 24–59 months 200,000 2 ml Every 6 months (biannual rounds)
First dose at 9 completed months (co-administered with measles/MR vaccine)
Subsequent doses every 6 months up to 59 months
Oral oil-based preparation (100,000 IU/ml syrup)
Not given below 6 months or above 5 years routinely
Implementation Strategy
Delivery Platforms :
Routine Immunization sessions (fixed & outreach)
Village Health Sanitation & Nutrition Days (VHSND)
Anganwadi Centers (ICDS)
ASHA home visits & MCP card tracking
Special biannual Vitamin A supplementation rounds (2 fixed days per year)
Service Providers : ANM, ASHA, AWW – trained on administration, contraindications & recording
Supply Chain : Vitamin A syrup supplied free through NHM; cold-chain not required (stable at room temperature)
Contraindications : None for prophylaxis; defer only in acute illness with vomiting or known hypervitaminosis
Counseling : Mothers advised on side-effects (transient vomiting, bulging fontanelle – rare), benefits & next due date
Integration with National Programs
Routine Immunization & MR campaign : First dose linkage mandatory
National Deworming Day : Often co-administered with Albendazole
MCP Card : Recording of each dose with date & batch number
POSHAN Abhiyaan & Anemia Mukt Bharat : Synergistic with micronutrient supplementation
IMNCI & HBNC : VAD screening & supplementation in sick-child management
Rashtriya Bal Swasthya Karyakram (RBSK) : Referral of clinical VAD cases
Facility-based care of SAM : Therapeutic Vitamin A as per WHO protocol for severe acute malnutrition
Monitoring & Evaluation
Indicators : Coverage of ≥2 doses in last 6 months (NFHS-5: ~71% national average)
Tools: MCP Card, RCH portal / MCTS, HMIS reporting, rapid coverage evaluation surveys
Supervision: District & block monitoring; supervisory checklists
Adverse event reporting: Through pharmacovigilance system (rare)
Impact & Evidence
Significant decline in clinical VAD & childhood blindness
Reduces all-cause under-5 mortality by 12–24% in deficient populations (WHO evidence)
Contributes to India’s progress towards SDG 2 & 3 targets
Cost-effective intervention (high return on investment)
Current focus (2024–26): Improve last-mile coverage in hard-to-reach areas, urban slums & migratory populations; linkage with digital tracking
🌱 This is a Digital Garden. Notes are always growing and changing.
These notes are intended for educational purposes only and reflect my personal understanding of the subject. Please cross-reference with standard textbooks and current clinical guidelines.
Authored by Dr. Rubanbalaji 2026