Definition And Pathogenesis

  • Classified within obsessive-compulsive and related disorders category.
  • Represents acute reactional process related to emotional stress or habitual behavior in young children.
  • Manifests as severe psychiatric disorder primarily in adolescents.

Diagnostic Criteria

  • Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition outlines specific criteria.
  • Visible hair loss directly attributable to pulling.
  • Mounting tension preceding or during hair pulling.
  • Gratification or tension release following hair pulling.
  • Absence of hallucinations, delusions, or inflammatory skin conditions explaining behavior.

Clinical Manifestations

  • Compulsive pulling, twisting, and breaking produces irregular areas of incomplete hair loss.
  • Favors crown, occipital, and parietal scalp regions.
  • Eyebrows, eyelashes, and body hair occasionally traumatized.
  • Behavior typically begins during inactivity (watching television, going to bed) and remains unobserved by parents.
  • Remaining hairs exhibit variable lengths and blunt tips secondary to breakage.
  • Scalp generally appears normal; however, hemorrhage, crusting, and chronic folliculitis occasionally occur.
  • Long-term repetitive trauma provokes irreversible follicular damage and permanent alopecia.
  • Trichophagy complication frequently produces trichobezoars.

Differential Diagnosis And Clinical Clues

Diagnostic FeatureTrichotillomaniaAlopecia AreataTinea Capitis
PatternIrregular pattern with mixed length and stubbly hairs.Circular or oval patches.Broken hairs at scalp surface (black-dot).
Specific Hair CluesBlunt-tipped broken hairs.Exclamation-point hairs.None.
Scalp SurfaceNormal; occasional hemorrhage or crusting.Normal.Scaling, pustules, or kerion.
Hair-Pull TestConsistently negative.Usually negative.Negative.
Associated ConditionsAnxiety or obsessive-compulsive tendencies.Nail pitting or grooves.Not applicable.

Management Protocol

  • Therapy directly targets underlying obsessive-compulsive disorder.
  • Pharmacologic options include clomipramine 50 to 150 mg/day.
  • Selective serotonin reuptake inhibitors including fluoxetine provide therapeutic benefit.
  • Efficacy maximized when combining pharmacotherapy with behavioral interventions.
  • N-Acetylcysteine demonstrates potential adjunctive utility.